Concanamycin E

Concanamycin E is a lysosomal acidification inhibitor with an IC50 value of 0.038 nM[1].

Product Specifications

CAS Number

[144450-35-1]

UNSPSC

12352005

Target

Proton Pump

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Inflammation/Immunology

Smiles

O=C1O[C@H]([C@@H](C)[C@@H](O)[C@@H]([C@@]2(O)C[C@@H](O[C@H]3C[C@H]([C@@H]([C@@H](C)O3)OC(N)=O)O)[C@H](C)[C@@H](/C=C/C)O2)C)[C@@H](OC)/C=C/C=C(C)/C[C@@H](C)[C@H](O)C[C@H](O)[C@H](C)/C=C(C)/C=C1\OC

Molecular Formula

C44H71NO14

Molecular Weight

838.03

References & Citations

[1]Woo JT, et al. Isolation, characterization and biological activities of concanamycins as inhibitors of lysosomal acidification. J Antibiot (Tokyo) . 1992 Jul;45 (7) :1108-16.