Cochleamycin A
Cochleamycin A showed strong inhibitory activity against tumor cells, with IC50s (μg/mL) of P388, HL60, K562, COL0205 and HT29 cells of 1.6, 14.0, 6.2, 16.5 and 19.1, respectively. Cochleamycin A also has anti-Gram-positive bacteria activity[1].
Product Specifications
CAS Number
134769-19-0
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
CC(O[C@@H]1[C@]2([H])[C@@](C[C@@H]1C)([H])[C@]3([H])[C@](C[C@H](C[C@]4([H])CC(/C(C(O4)=O)=C\3)=O)O)([H])C=C2)=O
Molecular Formula
C21H26O6
Molecular Weight
374.43
References & Citations
[1]Thomas A Dineen, et al. Total synthesis of cochleamycin A. Org Lett. 2004 Jun 10;6 (12) :2043-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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