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Phenazostatin A

Phenazostatin A is a phenazine Substance that has the protective effect of new neuron cells. Phenazostatin A can scavenge free radicals, protect N18-RE 105 nerve cells from glutamate toxicity, and inhibit lipid peroxidation. Phenazostatin A inhibits glutamate toxicity in N18-RE-105 cells with an EC50 of 0.34 μg/mL[1].

Product Specifications

CAS Number

[185614-22-6]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Neurological Disease

Smiles

O=C(C1=CC=CC2=NC3=C(C(C)OC4=CC=C5N=C6C=CC=CC6=NC5=C4)C=CC=C3N=C21)OC

Molecular Formula

C28H20N4O3

Molecular Weight

460.48

References & Citations

[1]W G Kim, et al. New diphenazines with neuronal cell protecting activity, phenazostatins A and B, produced by Streptomyces sp. J Antibiot (Tokyo) . 1997 Sep;50 (9) :715-21.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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