Fleephilone
Fleephilone is a fungal metabolite that can be isolated from Trichoderma harzianum. Fleephilone is a HIV REV/RRE binding inhibitor. Fleephilone inhibits the binding of REV-protein to RRE RNA with an IC50 of 7.6 μM[1].
Product Specifications
CAS Number
[183239-76-1]
UNSPSC
12352005
Target
Endogenous Metabolite; HIV
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
C/C=C/C=C/C1=C2[C@]3([H])[C@@]([C@H](CCN3C=C4C2=CC(C(C)(C4=O)OC(CC(O)C)=O)=O)O)([H])O1
Molecular Formula
C24H27NO7
Molecular Weight
441.47
References & Citations
[1]Qian-Cutrone J, et al. Harziphilone and fleephilone, two new HIV REV/RRE binding inhibitors produced by Trichoderma harzianum. J Antibiot (Tokyo) . 1996 Oct;49 (10) :990-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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