Manumycin F
Manumycin F has anti-Gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-Gram-negative bacteria, and has no effect on fungi. Manumycin F inhibits RAS Faraday base transfer and has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL) [1].
Product Specifications
CAS Number
156317-47-4
UNSPSC
12352211
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NC1=CC(/C=C/C=C/C=C/C(NC2=C(O)CCC2=O)=O)(C3OC3C1=O)O)/C=C/C=C/C=C/C4CCCCC4
Molecular Formula
C31H34N2O7
Molecular Weight
546.61
References & Citations
[1]Y Z Shu, et al. Manumycins E, F and G, new members of manumycin class antibiotics, from Streptomyces sp. J Antibiot (Tokyo) . 1994 Mar;47 (3) :324-33.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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