Manumycin F

Manumycin F has anti-Gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-Gram-negative bacteria, and has no effect on fungi. Manumycin F inhibits RAS Faraday base transfer and has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL) [1].

Product Specifications

CAS Number

[156317-47-4]

UNSPSC

12352211

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(NC1=CC(/C=C/C=C/C=C/C(NC2=C(O)CCC2=O)=O)(C3OC3C1=O)O)/C=C/C=C/C=C/C4CCCCC4

Molecular Formula

C31H34N2O7

Molecular Weight

546.61

References & Citations

[1]Y Z Shu, et al. Manumycins E, F and G, new members of manumycin class antibiotics, from Streptomyces sp. J Antibiot (Tokyo) . 1994 Mar;47 (3) :324-33.