Manumycin E
Manumycin E has anti-Gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-Gram-negative bacteria, and has no effect on fungi. Manumycin E inhibits RAS Faraday base transfer and has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL) [1].
Product Specifications
CAS Number
156250-43-0
UNSPSC
12352211
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C1C(NC(/C=C/C=C/C=C/[C@]2([C@@]3([H])[C@](C(C(NC(/C=C/C=C/C=C/CCC(C)C)=O)=C2)=O)([H])O3)O)=O)=C(O)CC1
Molecular Formula
C30H34N2O7
Molecular Weight
534.60
References & Citations
[1]Y Z Shu, et al. Manumycins E, F and G, new members of manumycin class antibiotics, from Streptomyces sp. J Antibiot (Tokyo) . 1994 Mar;47 (3) :324-33.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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