Hibarimicin G

Hibarimicin G is a tyrosine kinase inhibitor found in Microbispora rosea subsp. Hibaria[1].

Product Specifications

CAS Number

[208588-90-3]

UNSPSC

12352211

Target

Src

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Infection

Smiles

CCCC12C3(C(C(C(C2O[C@@H]4O[C@@H]([C@H](CC4)O[C@H]5C[C@H]([C@](O)([C@@H](O5)C)C(C)=O)O)C)O)O[C@H]6C[C@H]([C@H]([C@@H](O6)C)O)O)([H])C(C7=C(O)C(C(C(OC)=C(C8=C(C(OC)=C9C(C(O)=C%10C(CC%11([H])C(C%10=O)(C(O)(C(C(C%11O[C@H]%12C[C@H]([C@H]([C@@H](O%12)C)O)O)O)O[C@@H]%13O[C@@H]([C@H](CC%13)O[C@H]%14C[C@H]([C@](O)([C@@H](O%14)C)C(C)=O)O)C)CCC)O)=C9)=C8O)OC)C%15=O)=O)=C%15C(O)=C7C3=O)([H])O1)O

Molecular Formula

C85H112O39

Molecular Weight

1757.78

References & Citations

[1]Sung Ig Cho, et al. Effects of hibarimicins and hibarimicin-related compounds produced by Microbispora on v-Src kinase activity and growth and differentiation of human myeloid leukemia HL-60 cells. J Antibiot (Tokyo) . 2002 Mar;55 (3) :270-8.