Epoxyquinomicin B

Epoxyquinomicin B is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin B exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida and Staphylococcus aureus with a MIC of 6.25-12.5 µg/mL. Epoxyquinomicin B exhibits cytotoxicity in cancer cell L1210 with IC50 of 16.3 µg/mL. Epoxyquinomicin B exhibits anti-inflammatory effects against collagen-induced arthritis[1].

Product Specifications

CAS Number

[175448-32-5]

UNSPSC

12352211

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Field of Research

Cancer; Infection; Inflammation/Immunology

Smiles

OC[C@]12[C@](C(C(NC(C3=C(C=CC=C3)O)=O)=CC2=O)=O)([H])O1

Molecular Formula

C14H11NO6

Molecular Weight

289.24

References & Citations

[1]Matsumoto N, et al., Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities. J Antibiot (Tokyo) . 1997 Nov;50 (11) :900-5.