Epoxyquinomicin A
Epoxyquinomicin A is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin A exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida and Staphylococcus aureus with a MIC of 3-12.5 µg/mL. Epoxyquinomicin A exhibits cytotoxicity in cancer cell L1210, B16 and S180 with IC50 of 2-8 µg/mL. Epoxyquinomicin A exhibits anti-inflammatory effects against collagen-induced arthritis[1].
Product Specifications
CAS Number
[175448-31-4]
UNSPSC
12352211
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Cancer; Infection; Inflammation/Immunology
Smiles
OC[C@]12[C@](C(C(NC(C3=C(C(Cl)=CC=C3)O)=O)=CC2=O)=O)([H])O1
Molecular Formula
C14H10ClNO6
Molecular Weight
323.69
References & Citations
[1]Matsumoto N, et al., Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities. J Antibiot (Tokyo) . 1997 Nov;50 (11) :900-5.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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