Epicorazine B

Epicorazine B has activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MICs of 12.5-25 μg/mL. Epicorazine B also has effect on Candida albicans with a MIC of 25 μg/mL[1].

Product Specifications

CAS Number

[69176-72-3]

UNSPSC

12352005

Target

Bacterial; Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C1[C@@]23N(C([C@@]4(SS3)N1[C@@]5([H])[C@](C(C=C[C@@H]5O)=O)([H])C4)=O)[C@@]6([H])[C@@](C(C=C[C@@H]6O)=O)([H])C2

Molecular Formula

C18H16N2O6S2

Molecular Weight

420.46

References & Citations

[1]G Deffieux, et al. New antibiotics from the fungus Epicoccum nigrum. III. Epicorazine B: structure elucidation and absolute configuration. J Antibiot (Tokyo) . 1978 Nov;31 (11) :1106-9.