Diperamycin

Diperamycin has activity against Gram-positive bacteria, including Enterococcus seriolicida and MRSA (MICs of 0.10-0.20 μg/mL) . Diperamycin also strongly inhibits the activity of L1210, P388, LS-180, KB, HeLaS3, Meth A and B16-BL6 (IC50s of 0.009-0.098 μg/mL) [1].

Product Specifications

CAS Number

[220766-06-3]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Smiles

O=C1N2C(CCCN2)([H])C(N(C(C(NCC(N3C(CCCN3)([H])C(N(C(C(OC(C1NC(C(O)(C4(OC(C(CC4)CCCCCC)C)O)C)=O)C)=O)C)O)=O)=O)=O)COC)O)=O

Molecular Formula

C38H64N8O14

Molecular Weight

856.96

References & Citations

[1]N Matsumoto, et al. Diperamycin, a new antimicrobial antibiotic produced by Streptomyces griseoaurantiacus MK393-AF2. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo) . 1998 Dec;51 (12) :1087-92.