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Diazaquinomycin A

Diazaquinomycin A (DAQA), a diaza-anthracene antibiotic, is a thymidylate synthase inhibitor. Diazaquinomycin A (DAQA) induces DNA damage, cell cycle arrest, and apoptosis through cleaved-PARP[1].

Product Specifications

CAS Number

87614-40-2

UNSPSC

12352005

Target

Apoptosis; Thymidylate Synthase

Related Pathways

Apoptosis

Field of Research

Cancer

Smiles

O=C1NC(C(C(N2)=C3C(CCC)=C(C)C2=O)=O)=C(C(CCC)=C1C)C3=O

Molecular Formula

C20H22N2O4

Molecular Weight

354.40

References & Citations

[1]Michael W Mullowney, et al. Diazaquinomycins E-G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp. Mar Drugs. 2014 Jun 11;12 (6) :3574-86.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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