Cremimycin

Cremimycin has anti-Gram-positive bacteria activity including methicillin-resistant Staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. Cremimycin shows cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro[1].

Product Specifications

CAS Number

[182285-29-6]

UNSPSC

12352211

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Smiles

OC1=C2C(/C=C(/C=C/C=C/C(NC(CC(CCCC(CC2=O)O)=O)CCCCCC)=O)C)([H])CC1OC3CC(C(C(O3)C)O)OC

Molecular Formula

C35H53NO9

Molecular Weight

631.80

References & Citations

[1]M Igarashi, et al. Cremimycin, a novel 19-membered macrocyclic lactam antibiotic, from Streptomyces sp. J Antibiot (Tokyo) . 1998 Feb;51 (2) :123-9.