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Dioxamycin

Dioxamycin has anti-Gram-positive bacterial activity. Dioxamycin can inhibit Staphylococcus aureus 209P with a MIC of 3.12 μg/mL. Dioxamycin inhibits the growth of L1210, P388, IMC, LX-1 and SC-6 cells with IC50s (μg/mL) of 2.7, 1.4, 6.0, 2.0 and 2.5, respectively[1].

Product Specifications

CAS Number

[134861-62-4]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Smiles

O[C@@]12C3=C(C=C[C@@]1(C[C@@](O)([C@H](C2=O)O)C)O)C(C4=C(O)C([C@@H]5O[C@@H]([C@H](CC5)OC(/C=C/C=C/C=C/[C@@H]6O[C@](C)(O[C@H]6C)C(O)=O)=O)C)=CC=C4C3=O)=O

Molecular Formula

C38H40O15

Molecular Weight

736.72

References & Citations

[1]R Sawa, et al. Dioxamycin, a new benz[a]anthraquinone antibiotic. J Antibiot (Tokyo) . 1991 Apr;44 (4) :396-402.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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