Cystothiazole A

Cystothiazole A has antifungal activity. Cystothiazole A can inhibit candida albicans, saccharomyces cerevisiae and aspergillus smoke with MIC values of 0.4 μg/mL, 0.1 μg/mL and 1.6 μg/mL, respectively. Cystothiazole A also inhibits human tumor cell, such as HPT-116 and K562 cells with MIC values of 130 ng/mL and 110 ng/mL, respectively. Cystothiazole A has no anti-bacterial effect[1].

Product Specifications

CAS Number

[207399-36-8]

UNSPSC

12352005

Target

Fungal

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Smiles

COC(/C=C(OC)\[C@H](C)[C@@H](OC)/C=C/C1=CSC(C2=CSC(C(C)C)=N2)=N1)=O

Molecular Formula

C20H26N2O4S2

Molecular Weight

422.56

References & Citations

[1]Yoshihiro Suzuki, et al. Biotransformation of cystothiazole A, a myxobacterial antibiotic, into novel derivatives by the mother producer, Cystobacter fuscus. Biosci Biotechnol Biochem. 2004 Feb;68 (2) :390-6.