Cyclothialidine E
Cyclothialidine E inhibits escherichia coli DNA helicases with an IC50 of 0.7 μM[1].
Product Specifications
CAS Number
[194276-79-4]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
OC(CC[C@H](N)C(N1[C@@H]([C@@H](CC1)O)C(N[C@@H]2C(N[C@@H](CSCC3=C(O)C=C(O)C(C)=C3C(OC2)=O)C(N)=O)=O)=O)=O)=O
Molecular Formula
C25H33N5O11S
Molecular Weight
611.62
References & Citations
[1]N Nakada, et al. Biological characterization of cyclothialidine, a new DNA gyrase inhibitor. Antimicrob Agents Chemother. 1993 Dec;37 (12) :2656-61.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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