Chrolactomycin
Chrolactomycin is found in the strain of Streptomyces sp. 569N-3. The IC50 of Chrolactomycin for ACHN, A431, McF-7 and T24 cells are 1.2 μM, 1.6 μM, 0.69 μM and 0.45 μM, respectively. Chrolactomycin has only anti-Gram-positive bacteria activity with the MIC of 5.2-10.4 μg/mL[1].
Product Specifications
CAS Number
[227606-82-8]
UNSPSC
12352211
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
CO[C@@]12[C@]3([H])[C@@]4(OC2=O)[C@](CCC[C@H](C[C@H]([C@@](C(C1=O)=C)([H])O3)C)C)([H])C=C([C@H](C4)C)C(O)=O
Molecular Formula
C24H32O7
Molecular Weight
432.51
References & Citations
[1]R Nakai, et al. Chrolactomycin, a novel antitumor antibiotic produced by Streptomyces sp. J Antibiot (Tokyo) . 2001 Oct;54 (10) :836-9.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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