Avilamycin C

CC1=C(C(OC)=C(C(O)=C1Cl)Cl)C(O[C@@H]2[C@@H](C)O[C@@H](O[C@@H]3[C@@H](C)O[C@]4(O[C@]([C@@H]5O4)(C)C[C@H](O[C@H]6[C@@H](OC)[C@@H](C)O[C@@H](O[C@@H]7[C@@H](COC)O[C@@H](O[C@H]8[C@H](OC(C(C)C)=O)[C@H]9[C@@H](O[C@@]%10(O9)[C@H]%11[C@@H](OCO%11)[C@@]([C@@H](C)O%10)(C(C)O)O)CO8)[C@@H](OC)[C@H]7O)[C@@H]6O)O[C@@H]5C)C[C@H]3O)C[C@H]2O)=O

[1]Zhang D, et al. An NADH/NAD+-favored aldo-keto reductase facilitates avilamycin A biosynthesis by primarily catalyzing oxidation of avilamycin C. Appl Environ Microbiol. 2024 Apr 17;90 (4) :e0015024.|[2]Weitnauer G, et al. Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tü57 and production of new antibiotics. Chem Biol. 2001 Jun;8 (6) :569-81.