Alldimycin A

Alldimycin A is an anthracycline compound that inhibits RNA and DNA syntheses. Alldimycin A inhibits the growth, DNA and RNA synthesis of murine leukemic L1210, with IC50 values of 0.05 μg/mL, 0.92 μg/mL, and 0.47 μg/mL, respectively[1].

Product Specifications

CAS Number

[122397-46-0]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CN(C)[C@H]1C[C@@H](O[C@H]([C@H]1O)C)O[C@H](C2=CC3=C(C(C4=C(C3=O)C(O)=CC=C4O)=O)C(O)=C52)C[C@@]([C@@H]5O)(CC)O

Molecular Formula

C28H33NO10

Molecular Weight

543.56

References & Citations

[1]Johdo O, et al. Anthracycline metabolites from Streptomyces violaceus A262. V. New anthracycline alldimycin A: a minor component isolated from obelmycin beer. J Antibiot (Tokyo) . 1991 Oct;44 (10) :1160-4.