1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole

1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole (Compound 19) is a carbazole alkaloid that can be isolated from Murraya koenigii. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole exhibits anti-inflammatory and antimicrobial activities. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can inhibit the production of pro-inflammatory cytokines TNF-α and IL-6 . 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole has IC50 values of 10.9 μM and 95 μM for Bacillus cereus and Staphylococcus aureus, respectively. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can be used in the research of inflammatory and infectious diseases[1].

Product Specifications

CAS Number

[484678-79-7]

UNSPSC

12352005

Target

Bacterial; Interleukin Related

Related Pathways

Anti-infection; Immunology/Inflammation

Field of Research

Infection; Inflammation/Immunology

Smiles

O=CC1=CC(O)=C2NC3=C(C2=C1)C=CC(OC)=C3C/C=C(C)\C

Molecular Formula

C19H19NO3

Molecular Weight

309.36

References & Citations

[1]Nalli Y, et al. Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities. Org Biomol Chem. 2016 Mar 28;14 (12) :3322-32.