Centaurein
Centaurein, a flavonoid, is an IFN-γ promoter enhancer. Centaurein up-regulates the activity of NFAT and NF-κB enhancers. Centaurein increases the IFN-γ expression in T and NK cells and the serum IFN-γ level in mice. Centaureidin completely relaxes the contractions in intact rat aortic rings. Centaurein effectively protects mice against Listeria infection[1][2][3][4].
Product Specifications
CAS Number
35595-03-0
UNSPSC
12352005
Target
Bacterial; IFNAR; NF-κB; Nuclear Factor of activated T Cells (NFAT)
Related Pathways
Anti-infection; Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Smiles
O=C1C2=C(O)C(OC)=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)C=C2OC(C4=CC(O)=C(C=C4)OC)=C1OC
Molecular Formula
C24H26O13
Molecular Weight
522.46
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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