4'-Methoxyisoagarotetrol

4'-Methoxyisoagarotetrol is chromone derivative and shows moderate PDE 3A inhibitory activity (IC50=54 μM) [1].

Product Specifications

CAS Number

[104901-10-2]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Solubility

10 mM in DMSO

Smiles

O=C1C2=C([C@@H]([C@H]([C@@H]([C@H]2O)O)O)O)OC(CCC3=CC=C(C=C3)OC)=C1

Molecular Formula

C18H20O7

Molecular Weight

348.35

References & Citations

[1]Sugiyama, Takuji; Narukawa, Yuji; Shibata, Shunsuke; Masui, Ryo; Kiuchi, Fumiyuki (2018) . Three new 5,6,7,8-tetrahydroxy-5,6,7,8-tetrahydrochromone derivatives enantiomeric to agarotetrol from agarwood. Journal of Natural Medicines. 2018 Jun;72 (3) :667-674