Ignavine
Ignavine is a conformational modulator of μ-opioid receptors (IC50 = 2.0 μM) . Ignavine exhibits a concentration dependent bidirectional regulatory effect in vitro. Ignavine has analgesic activity. Ignavine can be used for research on pain related conditions[1].
Product Specifications
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Inflammation/Immunology
Smiles
O[C@]1(C[C@]2([H])C3)[C@@]4(C[C@H]5OC(C6=CC=CC=C6)=O)[C@@]([N@@]7C8)([H])[C@]3([H])[C@]1([C@@H](C2=C)O)C[C@@]7([H])[C@]4([H])[C@]8([C@H]5O)C
Molecular Formula
C27H31NO5
Molecular Weight
449.54
References & Citations
[1]Ohbuchi K, et al. Ignavine: a novel allosteric modulator of the μ opioid receptor. Sci Rep. 2016 Aug 17;6:31748.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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