(Z) -Ganoderenic acid K

(Z) -Ganoderenic acid K is a triterpene acid that can be isolated from the basidiocarp of Ganoderma lucidum. Ganoderenic acid K (HY-N11637), the isomer of (Z) -Ganoderenic acid K, is a HMG-CoA reductase (HMGCR) inhibitor with an IC50 of 16.5 μM[1].

Product Specifications

CAS Number

[1910062-54-2]

UNSPSC

12352211

Target

HMG-CoA Reductase (HMGCR)

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

C[C@@]12[C@]([C@@H](C(C3=C1[C@H](C[C@]4([H])[C@@]3(CC[C@@H](C4(C)C)O)C)O)=O)OC(C)=O)([C@H](CC2=O)/C(C)=C\C(C[C@@H](C)C(O)=O)=O)C

Molecular Formula

C32H44O9

Molecular Weight

572.69

References & Citations

[1]Hennicke F, et al. Distinguishing commercially grown Ganoderma lucidum from Ganoderma lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles. Phytochemistry. 2016 Jul;127:29-37.