(Z) -Ganoderenic acid K
(Z) -Ganoderenic acid K is a triterpene acid that can be isolated from the basidiocarp of Ganoderma lucidum. Ganoderenic acid K , the isomer of (Z) -Ganoderenic acid K, is a HMG-CoA reductase (HMGCR) inhibitor with an IC50 of 16.5 μM[1].
Product Specifications
CAS Number
1910062-54-2
UNSPSC
12352211
Target
HMG-CoA Reductase (HMGCR)
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
C[C@@]12[C@]([C@@H](C(C3=C1[C@H](C[C@]4([H])[C@@]3(CC[C@@H](C4(C)C)O)C)O)=O)OC(C)=O)([C@H](CC2=O)/C(C)=C\C(C[C@@H](C)C(O)=O)=O)C
Molecular Formula
C32H44O9
Molecular Weight
572.69
References & Citations
[1]Hennicke F, et al. Distinguishing commercially grown Ganoderma lucidum from Ganoderma lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles. Phytochemistry. 2016 Jul;127:29-37.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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