Tetrahydroamentoflavone
Tetrahydroamentoflavone (Amentoflavanone) is a potent xanthine oxidase (XO) inhibitor. Tetrahydroamentoflavone has inhibitory activity for XO with IC50 and Ki values of 92 nM and 0.982 μM, respectively. Tetrahydroamentoflavone can be used for the research of inflammatory disorders and gout[1].
Product Specifications
CAS Number
48236-96-0
Product Name Alternative
Amentoflavanone
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Xanthine Oxidase
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
OC1=CC(O)=C(C(C[C@@H](C2=CC=C(C=C2)O)O3)=O)C3=C1C4=CC([C@H]5OC6=CC(O)=CC(O)=C6C(C5)=O)=CC=C4O
Molecular Formula
C30H22O10
Molecular Weight
542.49
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]Ranjith Arimboor, et al. Tetrahydroamentoflavone (THA) from Semecarpus anacardium as a potent inhibitor of xanthine oxidase. J Ethnopharmacol. 2011 Feb 16;133 (3) :1117-20.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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