(-) -Codonopsine
(-) -Codonopsine is an alkaloid that can be found in Codonopsis clematidea. It has antibacterial and hypotensive activities. The MIC value of (-) -Codonopsine against Escherichia coli (E. coli) is 64 μg/mL. (-) -Codonopsine is expected to be used in the research of anti-infection and cardiovascular fields[1][2].
Product Specifications
CAS Number
26989-20-8
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease
Smiles
O[C@@H]1[C@H](N([C@@H]([C@H]1O)C)C)C2=CC(OC)=C(C=C2)OC
Molecular Formula
C14H21NO4
Molecular Weight
267.32
References & Citations
[1]Iida H, et al. Stereochemical revision and absolute configuration of codonopsinine[J]. Tetrahedron letters, 1986, 27 (44) : 5393-5396.|[2]El-Nezhawy AOH, et al. Design and total synthesis of (-) -codonopsinine, (-) -codonopsine and codonopsinine analogues by O- (2-oxopyrrolidin-5-yl) trichloroacetimidate as amidoalkylating agent with improved antimicrobial activity via solid lipid nanoparticle formulations. Bioorg Med Chem. 2019 Apr 1;27 (7) :1263-1273.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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