Bilirubin diglucuronide

Bilirubin diglucuronide is the metabolite of Bilirubin (HY-N0323) . Bilirubin diglucuronide inhibits MRP1/2 mediated ATP-dependent transport of leukotriene C4 (LTC4) in membrane vesicles[1].

Product Specifications

CAS Number

[17459-92-6]

UNSPSC

12352005

Target

Drug Metabolite; P-glycoprotein

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC(CCC(C(C)=C(N2)/C=C3C(C=C)=C(C(N/3)=O)C)=C2CC4=C(C(C)=C(N4)/C=C5C(C)=C(C(N/5)=O)C=C)CCC(O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)=O)=O)=O

Molecular Formula

C45H52N4O18

Molecular Weight

936.91

References & Citations

[1]Jedlitschky G, et al., ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. Biochem J. 1997 Oct 1;327 (Pt 1) (Pt 1) :305-10.