Santacruzamate A (Standard)

Santacruzamate A (Standard) is the analytical standard of Santacruzamate A. This product is intended for research and analytical applications. Santacruzamate A (CAY-10683, STA) is a potent and selective HDAC2 inhibitor with an IC50 of 119 pM. STA also exerts neuroprotective property against amyloid-β protein fragment 25–35. STA can be used for cancer and neurological disease research[1][2].

Product Specifications

CAS Number

[1477949-42-0]

Product Name Alternative

CAY-10683 (Standard)

UNSPSC

12352005

Target

Amyloid-β; HDAC; Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; Neuronal Signaling; Others

Field of Research

Cancer; Neurological Disease

Smiles

O=C(OCC)NCCCC(NCCC1=CC=CC=C1)=O

Molecular Formula

C15H22N2O3

Molecular Weight

278.35

References & Citations

[1]Pavlik CM, et al. Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. J Nat Prod. 2013 Nov 22;76 (11) :2026-33.