Manninotriose (Standard)
Wy-45494 (hydrochloride) (Standard) is the analytical standard of Wy-45494 (hydrochloride) . This product is intended for research and analytical applications. Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC50s of 4.7 and 1.6 μM, respectively) . In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg.
Product Specifications
CAS Number
13382-86-0
UNSPSC
12352005
Target
Endogenous Metabolite; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Smiles
O[C@@H]([C@@H](O)[C@H](O)[C@@H](O)C=O)CO[C@H]([C@@H]([C@@H](O)[C@H]1O)O)O[C@@H]1CO[C@H]([C@@H]([C@@H](O)[C@H]2O)O)O[C@@H]2CO
Molecular Formula
C18H32O16
Molecular Weight
504.44
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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