(3R,5R) -Octahydrocurcumin

(3R,5R) -Octahydrocurcumin (Compound 7) is gut microbial metabolite of Curcumin (HY-N0005) . (3R,5R) -Octahydrocurcumin exhibits neuroprotective efficacy against Aβ25-35-induced cell damage in SH-SY5Y, and anti-inflammatory activity against LPS-stimulated mouse microglial BV-2[1].

Product Specifications

CAS Number

[408324-14-1]

Product Name Alternative

(3R,5R) -Hexahydrobisdemethoxycurcumin

UNSPSC

12352005

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

COC(C=C1CC[C@@H](O)C[C@H](O)CCC2=CC(OC)=C(C=C2)O)=C(C=C1)O

Molecular Formula

C21H28O6

Molecular Weight

376.44

References & Citations

[1]Yang Y, et al., Neuroprotective and Anti-inflammatory Ditetrahydrofuran-Containing Diarylheptanoids from Tacca chantrieri. J Nat Prod. 2020 Dec 24;83 (12) :3681-3688.