(3R,5R) -Octahydrocurcumin
(3R,5R) -Octahydrocurcumin (Compound 7) is gut microbial metabolite of Curcumin (HY-N0005) . (3R,5R) -Octahydrocurcumin exhibits neuroprotective efficacy against Aβ25-35-induced cell damage in SH-SY5Y, and anti-inflammatory activity against LPS-stimulated mouse microglial BV-2[1].
Product Specifications
CAS Number
[408324-14-1]
Product Name Alternative
(3R,5R) -Hexahydrobisdemethoxycurcumin
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
COC(C=C1CC[C@@H](O)C[C@H](O)CCC2=CC(OC)=C(C=C2)O)=C(C=C1)O
Molecular Formula
C21H28O6
Molecular Weight
376.44
References & Citations
[1]Yang Y, et al., Neuroprotective and Anti-inflammatory Ditetrahydrofuran-Containing Diarylheptanoids from Tacca chantrieri. J Nat Prod. 2020 Dec 24;83 (12) :3681-3688.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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