Schisanchinin D
Schisanchinin D is an NO release inhibitor found in the fruits of Schisandra chinensis. Schisanchinin D can inhibit the release of nitric oxide (NO) by lipopolysaccharide (LPS) -activated microglia in primary murine BV2 microglia cells. Schisanchinin D is promising for research of neurodegenerative diseases such as Alzheimer's disease (AD) [1][2].
Product Specifications
CAS Number
1614245-13-4
UNSPSC
12352005
Target
NO Synthase
Related Pathways
Immunology/Inflammation
Field of Research
Neurological Disease
Smiles
OC1=C(OC)C(OC)=CC2=C1C3=C(OC)C(OC)=C(OC)C=C3C[C@H](C)[C@H](C)C2
Molecular Formula
C23H30O6
Molecular Weight
402.48
References & Citations
[1]Hu D, et al. Dibenzocyclooctadiene lignans from Schisandra chinensis and their inhibitory activity on NO production in lipopolysaccharide-activated microglia cells. Phytochemistry. 2014 Aug;104:72-8.|[2]Jafernik K, et al. Comprehensive review of dibenzocyclooctadiene lignans from the Schisandra genus: anticancer potential, mechanistic insights and future prospects in oncology. Chin Med. 2024 Jan 24;19 (1) :17.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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