Neferine (Standard)
Neferine (Standard) is the analytical standard of Neferine. This product is intended for research and analytical applications. Neferine is a major bisbenzylisoquinline alkaloid. Neferine strongly inhibits NF-κB activation.
Product Specifications
CAS Number
2292-16-2
UNSPSC
12352100
Target
Apoptosis; Autophagy; NF-κB; Reference Standards
Related Pathways
Apoptosis; Autophagy; NF-κB; Others
Field of Research
Metabolic Disease; Cancer
Smiles
OC1=CC=C(C[C@@H]2N(C)CCC3=C2C=C(OC)C(OC)=C3)C=C1OC4=CC5=C(C=C4OC)CCN(C)[C@@H]5CC6=CC=C(OC)C=C6
Molecular Formula
C38H44N2O6
Molecular Weight
624.77
References & Citations
[1]Baskaran R, et al. Neferine prevents NF-κB translocation and protects muscle cells from oxidative stress and apoptosis induced by hypoxia. Biofactors. 2016 Jul 8;42 (4) :407-17.|[2]Liu X, et al. Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice. Oncotarget. 2016 Sep 20;7 (38) :61703-61715.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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