4-Methylumbelliferone (sodium salt)

4-Methylumbelliferone (sodium salt) is a coumarin derivative. 4-Methylumbelliferone (sodium salt) can be used as a standard to quantify the free 4-methylumbelliferone released as a result of enzyme-substrate action. 4-Methylumbelliferone (sodium salt) inhibits hyaluronan production in vitro. 4-Methylumbelliferone (sodium salt) can be studied in ovarian cancer research[1][2][3].

Product Specifications

CAS Number

[5980-33-6]

Product Name Alternative

Hymecromone (sodium salt) ; 4-MU (sodium salt)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Biochemical Assay Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

O=C1C=C(C2=CC=C(C=C2O1)O[Na])C

Molecular Formula

C10H7NaO3

Molecular Weight

198.15

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Pibuel, M. A., et al., (2021) . 4-Methylumbelliferone as a potent and selective antitumor drug on a glioblastoma model. Glycobiology, 31 (1), 29–43.|[2]Rodrigues, A. C., (2015) . Celluclast and Cellic® CTec2: Saccharification/fermentation of wheat straw, solid-liquid partition and potential of enzyme recycling by alkaline washing. Enzyme and microbial technology, 79-80, 70–77. |[3]Lokman, N. A., et al., (2019) . 4-Methylumbelliferone Inhibits Cancer Stem Cell Activation and Overcomes Chemoresistance in Ovarian Cancer. Cancers, 11 (8), 1187.