(R) -Tetrahydropapaverine (hydrochloride)

(R) -Tetrahydropapaverine hydrochloride is the isomer of Tetrahydropapaverine hydrochloride (HY-N0137), and can be used as an experimental control. Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons[1][2].

Product Specifications

CAS Number

[54417-53-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=CC2=C(C=C1OC)CCN[C@@H]2CC3=CC=C(OC)C(OC)=C3.[H]Cl

Molecular Formula

C20H26ClNO4

Molecular Weight

379.88

Precautions

H302, H315, H319, H335

References & Citations

[1]Koshimura I, et al. Dimethoxyphenylethylamine and tetrahydropapaverine are toxic to the nigrostriatal system. Brain Res. 1997 Oct 31;773 (1-2) :108-16.|[2]Kim EI, et al. Inhibitory effects of tetrahydropapaverine on serotonin biosynthesis in murine mastocytoma P815 cells. Life Sci. 2004 Sep 3;75 (16) :1949-57.