(±) -Evodiamine (Standard)

(±) -Evodiamine (Standard) is the analytical standard of (±) -Evodiamine. This product is intended for research and analytical applications. (±) -Evodiamine, a quinazolinocarboline alkaloid, is a Top1 inhibitor. Evodiamine exhibits anti-inflammatory, antiobesity, and antitumor effects. (±) -Evodiamine inhibits the proliferation of a wide variety of tumor cells by inducing their apoptosis[1].

Product Specifications

CAS Number

[518-18-3]

UNSPSC

12352100

Target

Apoptosis; Reference Standards; Topoisomerase

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Others

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Smiles

O=C1C2=CC=CC=C2N(C)C(N1CC3)C4=C3C5=CC=CC=C5N4

Molecular Formula

C19H17N3O

Molecular Weight

303.36

References & Citations

[1]Dong G, et, al. New tricks for an old natural product: discovery of highly potent evodiamine derivatives as novel antitumor agents by systemic structure-activity relationship analysis and biological evaluations. J Med Chem. 2012 Sep 13;55 (17) :7593-613.