Betulin-d3-1

Betulin-d3-1 is the deuterium labeled Betulin (HY-N0083) . Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line.

Product Specifications

UNSPSC

12352211

Target

Apoptosis; Endogenous Metabolite; Fatty Acid Synthase (FASN) ; Isotope-Labeled Compounds

Related Pathways

Apoptosis; Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

[2H]C1([2H])[C@]([2H])(O)C(C)(C)C(CC[C@]2(C)[C@]3([H])CC[C@@]4([H])[C@@]2(C)CC[C@]5(CO)[C@]4([H])[C@H](C(C)=C)CC5)[C@]3(C)C1

Molecular Formula

C30H47D3O2

Molecular Weight

445.74

References & Citations

[1]Król SK, et al. Comprehensive review on betulin as a potent anticancer agent. Biomed Res Int. 2015;2015:584189.|[2]Drag M, et al. Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines. Molecules. 2009 Apr 24;14 (4) :1639-51.|[3]Ma C, et al. Protective effect of betulin on cognitive decline in streptozotocin (STZ) -induced diabetic rats. Neurotoxicology. 2016 Dec;57:104-111.