SGLT2-IN-1 (Standard)
SGLT2-IN-1 (standard) is the analytical standard for SGLT2-IN-1. This product is used for research and analytical applications. SGLT2-IN-1 (Compound 5) is an inhibitor for sodium-dependent glucose cotransporter (SGLT2), with IC50 of 33 nM in CHO cells transfected with human SGLT2. SGLT2-IN-1 is selective for SGLT2 over SGLT1. SGLT2-IN-1 is an active metabolite of dapagliflozinactive metabolite of dapagliflozin.
Product Specifications
CAS Number
[864070-37-1]
UNSPSC
12352005
Target
SGLT
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Metabolic Disease
Smiles
O[C@H]1[C@H](C2=CC(CC3=CC=C(C=C3)O)=C(C=C2)Cl)O[C@@H]([C@H]([C@@H]1O)O)CO
Molecular Formula
C19H21ClO6
Molecular Weight
380.82
References & Citations
[1]Lansdell MI, et al., Design and synthesis of fluorescent SGLT2 inhibitors. Bioorg Med Chem Lett. 2008 Sep 15;18 (18) :4944-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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