Flucofuron
Flucofuron exhibits high efficacy against trophozoites of both N. fowleri strains (ATCC 30808 : IC50 = 2.58 μM and ATCC 30215: IC50 = 2.47 μM), being even active against the resistant cyst stage (IC50 = 0.88 μM) . Flucofuron can induce cell apoptosis. Flucofuron can be used for the researches of infection and inflammation, such as Primary amoebic meningoencephalitis (PAM) [1].
Product Specifications
CAS Number
[370-50-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Purity
99.75
Smiles
O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)NC2=CC=C(Cl)C(C(F)(F)F)=C2
Molecular Formula
C15H8Cl2F6N2O
Molecular Weight
417.13
Precautions
H302, H315, H319, H335
References & Citations
[1]Chao-Pellicer J, et al. Flucofuron as a Promising Therapeutic Agent against Brain-Eating Amoeba. ACS Infect Dis. 2024 Jun 14;10 (6) :2063-2073.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
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