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Tyk2 (JH1/JH2) Recombinant Human Active Protein Kinase

TYK2 is a member of the JAK family of non-receptor tyrosine kinases that act together with signal transducer and activator of transcription (STAT) factors in mediating intracellular signal transduction. JAKs are characterized by dual kinase domain: a tyrosine kinase domain (JH1) that is preceded by a pseudokinase domain (JH2) . Tyk2 (JH1/JH2) Recombinant Human Active Protein Kinase is a recombinant Tyk2 (JH1/JH2) protein that can be used to study Tyk2 (JH1/JH2) -related functions[1].

Product Specifications

UNSPSC

12352211

Target

JAK

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Field of Research

Cancer

Smiles

[Tyk2(JH1/JH2)RecombinantHumanActiveProteinKinase]

References & Citations

[1]Min X, et al. Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2) . J Biol Chem. 2015 Nov 6;290 (45) :27261-27270.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Curated Selection

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