TYK2 (JH1) Recombinant Human Active Protein Kinase

TYK2 is a member of the JAK family of non-receptor tyrosine kinases that act together with signal transducer and activator of transcription (STAT) factors in mediating intracellular signal transduction. JAKs are characterized by dual kinase domain: a tyrosine kinase domain (JH1) that is preceded by a pseudokinase domain (JH2) . TYK2 (JH1) Recombinant Human Active Protein Kinase is a recombinant TYK2 (JH1) protein that can be used to study TYK2 (JH1) -related functions[1].

Product Specifications

UNSPSC

12352211

Target

JAK

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

[TYK2(JH1)RecombinantHumanActiveProteinKinase]

References & Citations

[1]Min X, et al. Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2) . J Biol Chem. 2015 Nov 6;290 (45) :27261-27270.