TRKA (NTRK1) Recombinant Human Active Protein Kinase

TRKA (also named NTRK1) is a potential new member of the tyrosine kinase gene family. TRKA is a receptor tyrosine kinase that is phosphorylated in response to NGF. A single transmembrane domain divides TRKA into an extracellular domain, important for NGF binding, and an intracellular tyrosine kinase domain, important for signal transduction. TRKA (NTRK1) Recombinant Human Active Protein Kinase is a recombinant TRKA (NTRK1) protein that can be used to study TRKA (NTRK1) -related functions[1].

Product Specifications

UNSPSC

12352211

Target

Trk Receptor

Related Pathways

Neuronal Signaling; Protein Tyrosine Kinase/RTK

Field of Research

Neurological Disease

Smiles

[TRKA(NTRK1)RecombinantHumanActiveProteinKinase]

References & Citations

[1]Mardy S, et al. Congenital insensitivity to pain with anhidrosis: novel mutations in the TRKA (NTRK1) gene encoding a high-affinity receptor for nerve growth factor. Am J Hum Genet. 1999 Jun;64 (6) :1570-9.