MAP2K1 L115P Recombinant Human Active Protein Kinase
MAP2K1 (also known as MEK1) is downstream of the RAF family and activation results in ERK1/2 activation. Activating mutations in MAP2K1 have been reported almost exclusively in exons 1 and 2 in both hematologic malignancies. MAP2K1 L115P is a mutant of MAP2K1. MAP2K1 L115P Recombinant Human Active Protein Kinase is a recombinant MAP2K1 L115P protein that can be used to study MAP2K1 L115P-related functions[1].
Product Specifications
UNSPSC
12352211
Target
MEK
Related Pathways
MAPK/ERK Pathway
Field of Research
Cancer
Smiles
[MAP2K1L115PRecombinantHumanActiveProteinKinase]
References & Citations
[1]McGinnis LM, et al. Frequency of MAP2K1, TP53, and U2AF1 Mutations in BRAF-mutated Langerhans Cell Histiocytosis: Further Characterizing the Genomic Landscape of LCH. Am J Surg Pathol. 2018 Jul;42 (7) :885-890.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
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