FGFR3 V555L Recombinant Human Active Protein Kinase

FGFR3 kinase mutations are associated with a variety of malignancies. FGFR3 V555L mutation leads to resistance to FGFR inhibitors. FGFR3 V555L Recombinant Human Active Protein Kinase is a recombinant FGFR3 V555L protein that can be used to study FGFR3 V555L-related functions[1].

Product Specifications

UNSPSC

12352211

Target

FGFR

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

[FGFR3V555LRecombinantHumanActiveProteinKinase]

References & Citations

[1]Liu B, et al. Elucidating the potential effects of point mutations on FGFR3 inhibitor resistance via combined molecular dynamics simulation and community network analysis. J Comput Aided Mol Des. 2023 Jul;37 (7) :325-338.