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TIE2 Y1108F Recombinant Human Active Protein Kinase

TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 Y1108F is the most mutation of TIE2. TIE2 Y1108F Recombinant Human Active Protein Kinase is a recombinant TIE2 Y1108F protein that can be used to study TIE2 Y1108F-related functions[1].

Product Specifications

UNSPSC

12352211

Target

Tie

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cardiovascular Disease

Smiles

[TIE2Y1108FRecombinantHumanActiveProteinKinase]

References & Citations

[1]Kennedy MA, et al. A Tie2 kinase mutation causing venous malformations increases phosphorylation rates and enhances cooperativity. Biochem Biophys Res Commun. 2019 Feb 19;509 (4) :898-902.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Curated Selection

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