JAK1 S729C Recombinant Human Active Protein Kinase
JAK1 belongs to Janus family kinases (JAK) family. JAK mediates the Stat activation by cytokines. Jak1 is involved in IL-6-stimulated Stat3 activity. JAK1S729C mutations is proved to be activating mutations in vitro. JAK1 S729C Recombinant Human Active Protein Kinase is a recombinant JAK1 S729C protein that can be used to study JAK1 S729C-related functions[1].
Product Specifications
UNSPSC
12352211
Target
JAK
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Cancer
Smiles
[JAK1S729CRecombinantHumanActiveProteinKinase]
References & Citations
[1]Shuqun Yang, et al. Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma. Oncotarget. 2016 Feb 2;7 (5) :5461-9.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
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