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INSR Recombinant Human Active Protein Kinase

The whole IGF axis constitutes an interactive network composed of the peptide-ligands IGF1, IGF2 and insulin, and the receptors IGF1R, IGF2R and insulin receptor (INSR) as IGF binding proteins (IGFBPs) . The INSR itself appears in two isoforms, INSRA and INSRB differing in 12 amino acids encoded by exon 11. INSR Recombinant Human Active Protein Kinase is a recombinant INSR protein that can be used to study INSR-related functions[1].

Product Specifications

UNSPSC

12352211

Target

IGF-1R

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Metabolic Disease

Smiles

[INSRRecombinantHumanActiveProteinKinase]

References & Citations

[1]Heidegger I, et al. Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis. Oncotarget. 2014 May 15;5 (9) :2723-35.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Curated Selection

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