INSR Recombinant Human Active Protein Kinase
The whole IGF axis constitutes an interactive network composed of the peptide-ligands IGF1, IGF2 and insulin, and the receptors IGF1R, IGF2R and insulin receptor (INSR) as IGF binding proteins (IGFBPs) . The INSR itself appears in two isoforms, INSRA and INSRB differing in 12 amino acids encoded by exon 11. INSR Recombinant Human Active Protein Kinase is a recombinant INSR protein that can be used to study INSR-related functions[1].
Product Specifications
UNSPSC
12352211
Target
IGF-1R
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Metabolic Disease
Smiles
[INSRRecombinantHumanActiveProteinKinase]
References & Citations
[1]Heidegger I, et al. Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis. Oncotarget. 2014 May 15;5 (9) :2723-35.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Curated Selection
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