FGFR4 V550E Recombinant Human Active Protein Kinase
FGFR4 is a transcriptional target of the PAX3-FOXO1 fusion gene. FGFR4 expression is significantly higher in rhabdomyosarcoma. FGFR4 V550E is a mutant of FGFR3 that may be present in rhabdomyosarcoma. FGFR4 V550E Recombinant Human Active Protein Kinase is a recombinant FGFR4 V550E protein that can be used to study FGFR4 V550EK-related functions[1].
Product Specifications
UNSPSC
12352211
Target
FGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
[FGFR4V550ERecombinantHumanActiveProteinKinase]
References & Citations
[1]Timothy McKinnon, et al. Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma. Oncogene. 2018 May;37 (20) :2630-2644.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
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