FGFR3 K650E Recombinant Human Active Protein Kinase

FGFR3 activating mutations are drivers of malignancy in several human tissues, including bladder, lung, cervix, and blood. FGFR3 K650E is a mutant of FGFR3 that may be present in multiple myeloma cell lines. FGFR3 K650E Recombinant Human Active Protein Kinase is a recombinant FGFR3 K650E protein that can be used to study FGFR3 K650E-related functions[1].

Product Specifications

UNSPSC

12352211

Target

FGFR

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

[FGFR3K650ERecombinantHumanActiveProteinKinase]

References & Citations

[1]Ronchetti D, et al. Deregulated FGFR3 mutants in multiple myeloma cell lines with t (4;14) : comparative analysis of Y373C, K650E and the novel G384D mutations. Oncogene. 2001 Jun 14;20 (27) :3553-62.